Biography
Nirav has completed his M.Pharm from Gujarat Technological University (GTU) and he has taken Post-Graduate Diploma Intellectual Property Rights (PGDIPR). He got “Best Teaching Award†and he has achieved award of “Best-Student of the year†for the year 2013. Recently, He got \"National Award\"- PEARL Foundation “Best Assistant Professor Award in Pharmacy†for the year 2016. Also, “International Young Leadership Awards-2016†- TIME CyberMedia Pvt. Ltd. “Best Upcoming Young Researcher in Ahmedabad†for the year 2016. He cracked GPAT (Graduate Pharmacy Aptitude Test-2013, AICTE) and got stipend from the Indian government. Research Experience in Bioanalytical department and published thesis. Also, He has published Books with ISBN. He has published research, review articles and letter to the editors in reputed International journals. He has been serving as an editorial board member as well as reviewers of reputes
Abstract
A simple, rapid, sensitive, and selective liquid chromatography-tandem mass spectrometry (MS) method was developed and validated for the quantification of Metaxalone, a skeletal muscle relaxant, in human plasma using Metaxalone –D6 as Internal Standard (IS). Following Liquid-Liquid Extraction (LLE) , the analytes were separated using an isocratic mobile phase on a reverse phase C18 column (Chromatopak peerless basic 50× 4.6mm× 3.0µm ) and analyzed by MS in the multiple reaction monitoring mode using the respective [M+H]+ ions, m/z 222.14 / 160.98 for Metaxalone and m/z 228.25 /167.02 for the IS. The assay exhibited a linear dynamic range of 25.19-2521.313 ng/mL for metaxalone in human plasma. The goodness of fit was consistently greater than 0.98 during the course of validation. The range of accuracy and precision of the back-calculated concentrations of the standard curve points was from 94.1 % to 104.4 % and 0.3 % to 5.6 % for metaxalone A run time of 2.0 min for each sample and injection volume is 5 µl . The validated method has been successfully used to analyze human plasma samples for application in pharmacokinetic, bioavailability, or bioequivalence studies.
Biography
Dr Shibani Datta is a Professor of Public Health in All India Institute of Hygiene and Public Health. Previously she was a Professor of Calcutta Medical College which is a very renowned College in West Bengal India . She was the team leader of Central Surveillance team of India. Many of her research works have been published in National and International journals.
Abstract
Diabetes is a silent killer of the century. It has been defined as Fasting blood glucose-126 mg/dl (7.0 mmol/L) and Post-prandial blood glucose-200 mg/dl (11.1 mmol/L). 1, 2 rnDiabetes mellitus causes silent but irreversible damage to different organ systems and It increases the chance of Cardiovascular diseases with very rapid progression.3rnIn India the prevalence of diabetes in adults was found to be 2.4 percent in rural and 4.0-11.6 percent in urban dwellers.1rnObjectives and methodology - A cross sectional observational study was done in a sample population of 235 slum dwellers to estimate the prevalence of diabetes mellitus , to determine the association of the biosocial risk factors and to assess the awareness among the study population . rnFindings - rn Prevalence of diabetes mellitus among the total study subjects was found to be 17.45% with prevalence of 20.93% among the female and 13.21% among the male.rn Awareness about diabetes mellitus was more in the female (8.53%) than male (6.6%).rnSignificant statistical association of diabetes mellitus was observed with age, marital status, physical exercise, diet, family history, obesity, hypertension and hypercholesterolemia.rnRecommendations rnRecommendations were made to adopt healthy life style by quitting addiction , reduction of obesity by diet control and regular physical activities etc rn